In some cases, it can lead to a situation in which even corneal transplantation is unsuccessful. Viral proteins synthesised in the cytoplasm are transferred to the nucleus where the nucleocapsid is assembled. Virologically, however, it’s a recurrence. Evidence now suggests that HSV-1 infection disrupts the normal equilibrium between angiogenic and anti-angiogenic stimuli leading to vascularisation. Data are the mean ± SEM. On the other hand, topical ganciclovir has been shown to be as safe and effective as acyclovir in the treatment of herpetic epithelial keratitis.
HSV type 1 (HSV-1) is primarily responsible for orofacial and ocular infections, whereas HSV type 2 (HSV-2) generally is transmitted sexually and causes genital disease. If it travels down the nerve to the eye, it may cause eye problems. Other more rare complications: corneal perforation, secondary glaucoma, systemic